Facial Herpes

Facial herpes is very common and is also known as cold sores, fever blisters, sun blisters, oro-facial herpes, herpes labialis and herpes febrilis. Facial herpes is characterised by groups of fluid-filled blisters that appear on the skin, in or around the nose and mouth. A burning or itching sensation is often present just before the skin lesions develop. The areas can be tender and painful. The blisters heal without scarring but they have a tendency to return.

These episodes are caused by a very common virus infection known as herpes simplex virus (HSV), of which there are two types:

  1. HSV-1, the most common type, which causes facial and genital herpes.
  2. HSV-2, which usually causes genital herpes.

The HSV virus invades the cells of the epidermis, the outer layer of skin, causing fluid-filled blisters to appear. The virus travels from the epidermis along the nerve paths to the trigeminal ganglion, a bundle of nerves close to the inner ear, where it lies hidden until it is reactivated. Potential triggers include a fever (for example, a common cold), UV radiation (exposure to sunlight), extreme tiredness or lowered immune function.

The initial infection

When a person is infected with herpes for the first time, the episode is called a primary infection. The primary infection can progress in different ways. Most will have no symptoms, some will have mild symptoms and some will experience discomfort. Sores can develop on the face, inside the nose or inside the mouth. When occurring in the mouth this is commonly called herpetic gingivostomatitis. Initially, this can take the form of painful sores affecting the mouth, gum, throat and lips, which may last for more than 14 days if left untreated. Herpetic gingivostomatitis should be treated with antiviral medicine. Most patients also require painkillers or even local anaesthetics, applied direct to the site, to ease the discomfort so that they can eat and drink.

This first outbreak usually starts 1–3 weeks after the virus has invaded the skin and may last 10-14 days (without antivirals), subsequent episodes known as recurrences may last 7-10 days (without antivirals).

Recurrences

The virus remains hidden in the nerves for the rest of the person’s life and becomes active again from time to time. Some people have few or no outbreaks while others have regular recurrences. They seem to become less frequent with age.

An outbreak has four stages:

  • A tingling feeling in the skin.
  • Slight swelling and then development of a cluster of fluid-filled blisters .which are often painful.
  • The blisters burst and leave ulcers/sores.
  • The sores eventually dry, scab over and heal without scarring after 8 to 10 days.

The virus can spread until the sores are completely covered by scabs and the infection will usually be external.

Sites of infection

Most commonly, herpes simplex affects the lips or nasal region, causing cold sores. Recurrences may affect the eye region or even involve the eye itself. Eye infection with HSV is also known by several other names, including: herpes keratitis, herpes conjunctivitis and herpes stromal keratitis. Deep infection of the eye is very rare, but can cause a syndrome called acute retinal necrosis. In children, the virus can infect the mouth and throat. The infection may be accompanied by a fever and general aches and pains.

What triggers facial herpes?

The factors which can trigger outbreaks differ from person to person. Trauma, fever, exposure to sunlight, extreme weather conditions, menstruation, or anything that lowers the immune system, such as a cold, flu or general illness, can cause reappearance in some people. In others, there is no obvious cause.

Transmitting facial herpes

People who experience an episode of herpes, either facial or genital, should consider themselves infectious from the start of the episode (i.e. tingling sensations) to the healing of the last ulcer. During this time the virus can be transmitted to other people and in rare cases, can be transferred to other areas of the body. Increasingly, genital herpes (genital HSV-1) is being caused by face-to-genital transmission. Remember, most of us acquire facial herpes in the first 5 years of our lives.

To help prevent transmission, you should avoid:

  • Kissing anyone or sharing, lip balms, drinking cups, drink bottles, or eating utensils when you have a cold sore present (normal washing and drying kills HSV-1 on cups/utensils)
  • Having oral sex when you or your partner have facial or genital sores.
  • Using saliva to wet contact lenses if you have sores around your mouth.
  • Sharing face flannels (although transmission during this route would be highly unlikely).

Hygiene is important for people infected with this virus. Try to avoid direct contact with the sores but if this does occur, wash your hands with soap and water and dry thoroughly. Avoid picking at the sores as this can spread the virus to other parts of the body or result in a bacterial infection of the sores. Avoid the use of harsh detergents on the affected skin.

The body’s defences can be strengthened by a healthy lifestyle. Try to eat a varied diet, exercise regularly and get enough sleep. Using a sunblock may help to prevent a recurrence in some cases.

How to diagnose facial herpes

Accurate diagnosis of facial herpes is made most easily and accurately at the time of an active herpes infection. A combination of the patient’s medical history and the appearance of the sores will usually be sufficient to identify facial herpes. A swab of the lesion can be used to confirm it.

Possible complications

  • The sores may become infected by bacteria.
  • The virus can spread to fingers, causing painful swelling and lesions (known as herpetic whitlow)
  • If the condition spreads to the eyes, in severe cases, it can damage vision (known as herpetic keratitis).
  • A very rare complication is swelling of the brain (known as encephalitis).
  • In patients who suffer from atopic dermatitis, in rare cases, the cold sores can spread to larger parts of the body (known as eczema herpeticum).
  • Massive cold sores can be a sign that another infection, pneumonia or HIV, for example, has weakened the body’s defences.

Treatment

Facial herpes may be treated, and sometimes even prevented, with an antiviral drug, valaciclovir, which is available as tablets (you need a health care professional or pharmacist prescription). There are also over-the-counter cold sore treatments your pharmacist can advise you about. Painkillers and a pain-relieving mouthwash may also ease the symptoms. The treatment should be started as soon as the first symptoms appear. Each episode can be treated with tablets or cream to speed the healing process. If episodes are very frequent or problematic, taking antiviral tablets daily may help prevent outbreaks.